Browsing Theses by Author "Suman, Evelyin"
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Characterizing the Associations and Roles of DDK and Mcm2-7 DNA Replication Proteins in Saccharomyces Cerevisiae
Suman, Evelyin (University of Waterloo, 2014-05-21)The essential cell cycle kinase Dbf4/Cdc7 (DDK) triggers DNA replication through phosphorylation of the Mcm2-7 helicase at replication origins. Prior work has implicated various Mcm2-7 subunits as targets of DDK, however ...