Browsing Theses by Author "Offman, Elliot"
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In-Silico Methods for De-Risking the Clinical Development of Subcutaneously Administered Therapeutic Macromolecules
Offman, Elliot (University of Waterloo, 2016-07-27)Prediction of human pharmacokinetics (PK) following subcutaneous (SC) administration to animals is challenged by potential interspecies differences in skin anatomy and physiology. With respect to biologic or macromolecule ...