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dc.contributor.authorLiu, Biwu
dc.contributor.authorHan, Xiao
dc.contributor.authorLiu, Juewen
dc.date.accessioned2017-04-28 16:11:58 (GMT)
dc.date.available2017-04-28 16:11:58 (GMT)
dc.date.issued2016-07-29
dc.identifier.urihttp://dx.doi.org/10.1039/c6nr02584f
dc.identifier.urihttp://hdl.handle.net/10012/11794
dc.description.abstractFluorescent polydopamine (FPD) is an interesting material with excellent biocompatibility. However, its preparation is currently a lengthy and potentially dangerous process. We herein employ magnetic iron oxide (Fe3O4) nanoparticles as a peroxidase-mimicking nanozyme to produce FPD under mild conditions. Different from previous protocols using multiple steps with up to 6% (similar to 2 M) H2O2, this preparation takes place in a single step with just 5 mM H2O2 at room temperature. The oxidized product shows excitation-wavelength-dependent emission peaks, similar to previous reports. The reaction kinetics, pH, temperature, and ionic strength are individually optimized. Among a diverse range of other nanomaterials tested, including Fe2O3, CeO2, CoO, Co3O4, NiO, TiO2, gold nanoparticles, and graphene oxide, Fe2O3 and graphene oxide yielded relatively weak emission, while the rest of the materials failed to produce FPD. The Fe3O4 nanoparticles retained similar to 90% catalytic activity even after ten cycles of synthesis. Finally, Zn2+ can enhance the fluorescence of FPD under 360 nm excitation but not under 480 nm excitation, leading to a sensitive light-up sensor with a detection limit of 60 nM Zn2+. Therefore, this work has demonstrated not only a novel use of nanozymes, but also an interesting application of FPD.en
dc.description.sponsorshipNatural Science and Engineering Research Council of Canada (NSERC); Chinese Scholarship Council (CSC)en
dc.language.isoenen
dc.publisherRoyal Society of Chemistryen
dc.subjectPeroxidase-Like Activityen
dc.subjectHydrogen-Peroxideen
dc.subjectArtificial Enzymesen
dc.subjectGlucose Detectionen
dc.subjectNanoparticlesen
dc.subjectDNAen
dc.subjectPoly(Dopamine)en
dc.subjectNanomaterialsen
dc.subjectDopamineen
dc.subjectDotsen
dc.titleIron oxide nanozyme catalyzed synthesis of fluorescent polydopamine for light-up Zn2+ detectionen
dc.typeArticleen
dcterms.bibliographicCitationLiu, B., Han, X., & Liu, J. (2016). Iron oxide nanozyme catalyzed synthesis of fluorescent polydopamine for light-up Zn2+ detection. Nanoscale, 8(28), 13620–13626. https://doi.org/10.1039/c6nr02584fen
uws.contributor.affiliation1Faculty of Scienceen
uws.contributor.affiliation2Chemistryen
uws.contributor.affiliation3Waterloo Institute for Nanotechnology (WIN)en
uws.typeOfResourceTexten
uws.peerReviewStatusRevieweden
uws.scholarLevelFacultyen


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