Now showing items 1-10 of 121
Regenerable DNA-Functionalized Hydrogels for Ultrasensitive, Instrument-Free Mercury(II) Detection and Removal in Water
(American Chemical Society, 2010-09-15)
Mercury is a highly toxic environmental pollutant with bioaccumulative properties. Therefore, new materials are required to not only detect but also effectively remove mercury from environmental sources such as water. We ...
Evaporation induced wrinkling of graphene oxide at the nanoparticle interface
(Royal Society of Chemistry, 2015-01-21)
With the thickness of only a single atomic layer, graphene displays many interesting surface properties. A general observation is that wrinkles are formed on graphene oxide (GO) when it is dried in the presence of adsorbed ...
Assembly of DNA-Functionalized Nanoparticles in Alcoholic Solvents Reveals Opposite Thermodynamic and Kinetic Trends for DNA Hybridization
(American Chemical Society, 2010-05-12)
DNA has been a key molecule in biotechnology and nanotechnology. To date, the majority of the experiments involving DNA have been performed in aqueous solutions, which may be related to the perception that DNA hybridization ...
Stimuli-responsive releasing of gold nanoparticles and liposomes from aptamer-functionalized hydrogels
(Institute of Physics, 2011-11-21)
Controlled release of therapeutic agents is important for improving drug efficacy and reducing toxicity. Recently, hydrogels have been used for controlled release applications. While the majority of the previous work focused ...
DNA-Functionalized Monolithic Hydrogels and Gold Nanoparticles for Colorimetric DNA Detection
(American Chemical Society, 2010-12-22)
Highly sensitive and selective DNA detection plays a central role in many fields of research, and various assay platforms have been developed. Compared to homogeneous DNA detection, surface-immobilized probes allow washing ...
Flow Cytometry-Assisted Detection of Adenosine in Serum with an Immobilized Aptamer Sensor
(American Chemical Society, 2010-05-15)
Aptamers are single-stranded nucleic acids that can selectively bind to essentially any molecule of choice. Because of their high stability, low cost, ease of modification, and availability through selection, aptamers hold ...
Fast Molecular Beacon Hybridization in Organic Solvents with Improved Target Specificity
(American Chemical Society, 2010-12-02)
DNA hybridization is of tremendous importance in biology, bionanotechnology, and biophysics. Molecular beacons are engineered DNA hairpins with a fluorophore and a quencher labeled on each of the two ends. A target DNA can ...
DNA Adsorption by Indium Tin Oxide (ITO) Nanoparticles
(American Chemical Society, 2015-01-13)
The high conductivity and optical transparency of indium tin oxide (ITO) has made it a popular material in the electronic industry. Recently, its application in biosensors is also explored. To understand its biointerface ...
DNAzyme Hybridization, Cleavage, Degradation and Sensing in Undiluted Human Blood Serum
(American Chemical Society, 2015-04-07)
RNA-cleaving DNAzymes provide a unique platform for developing biosensors. However, a majority of the work has been performed in clean buffer solutions, while the activity of some important DNAzymes in biological sample ...
Fast pH-assisted functionalization of silver nanoparticles with monothiolated DNA
(Royal Society of Chemistry, 2012-10-18)
Attaching monothiolated DNA to silver nanoparticles has been achieved at pH 3.0 in 30 minutes and difficulties associated with DNA attachment to AgNPs at neutral pH have been revealed by studying DNA adsorption kinetics.