Browsing University of Waterloo by Supervisor "Gu, Frank"
Now showing items 1-17 of 17
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Colorimetric Identification of Proteins Using Gold Nanoparticles
(University of Waterloo, 2016-05-31)Proteins are the principal executive biomolecules of life. Their existence is required to drive and regulate countless physiological and biochemical activities within the cell. The study of biochemistry and biology are ... -
Development of a topical ocular drug delivery system using polymeric nanoparticles
(University of Waterloo, 2016-04-01)Common eye diseases such as dry eye syndrome affect 15% of the population. Although eye drops are the most common treatment for these diseases, over 95% of the drugs applied through eye drops are quickly cleared away due ... -
Development of Microparticles Created from Physically Modified Starch Granules for the Uptake and Release of Drugs
(University of Waterloo, 2021-01-07)Controlled release drug delivery systems are, depending on the desired effect, generally an improvement over conventional drug delivery. Through material design, drugs can be delivered with temporal and spatial control, ... -
Development of Photocatalytic Materials and Systems for the Removal of Selenium from Industrially Impacted Water
(University of Waterloo, 2019-04-17)Selenium (Se) contaminated water derived from global industrial activities such as power generation, oil extraction and refining, coal and mineral mining, metal smelting, and agricultural irrigation can bioaccumulate in ... -
Double Emulsion Mucoadhesive Nanoparticles for Hydrophilic Ocular Drug Delivery
(University of Waterloo, 2018-09-05)Common eye diseases such as conjunctivitis affect around 6 million people annually. Although eye drops are the most common treatment for these diseases, topical administration is limited by low ocular bioavailability due ... -
The effectiveness of photocatalysis on reducing the toxicity of oil sands process-affected water to Lemna minor
(University of Waterloo, 2019-09-23)Oil sands process-affected water (OSPW) is a by-product produced by the surface-mining of oil sands in Alberta, Canada. OSPW has been found to be acutely and chronically toxic to many forms of wildlife, and due to the ... -
Flowable-Electrode Capacitive Deionization for Treatment of Mining Process-Affected Water
(University of Waterloo, 2019-11-26)Water is a critical resource in the mining and resources sector. It enables the extraction and materials processing operations that underpin this primary industry, and therefore everyday life. Water’s value in mining means ... -
Gold Surface Nanostructuring for Separation and Sensing of Biomolecules
(University of Waterloo, 2016-12-14)Detecting biomolecules in physiological environments is critical to health care and environmental monitoring. In this work, we study and use gold surfaces for biomolecule detection while incorporating nanoscale ... -
Immobilization of Gold Nanoparticles for Colourimetric and Ratiometric Refractive Index Sensing
(University of Waterloo, 2019-12-12)The development of refractive index sensors is an expanding field of research, with applications in fields including medical diagnostics, food safety and public health. Nanotechnology has become widely implemented in various ... -
Improving Biocompatibility of Implantable Bioelectronics using Zwitterionic Cysteine
(University of Waterloo, 2017-04-27)Recent advances in bioelectronics have allowed for faster diagnoses of diseases as well as treatments for disorders that were previously considered incurable. The performance of these devices is, however, severely hindered ... -
A Long-acting Ocular Lubricant Eye Drop based on Dextran Hydrogel Nanoparticles
(University of Waterloo, 2019-03-27)Dry eye disease is a highly prevalent condition that affects hundreds of millions of people worldwide. In moderate to severe cases, affected individuals experience considerable difficulty in carrying out their day-to-day ... -
Mucoadhesive Nanoparticles for Treatment of Influenza A
(University of Waterloo, 2017-08-31)Influenza A is the most pandemic-prone class of the influenza virus, with new strains emerging every year. Though vaccination is promoted as the vanguard against wide-spread infection, it is not enough to withstand mutating ... -
Nanoparticle Notch Filters for Selective Filtering of Blue Light in Contact Lenses
(University of Waterloo, 2018-08-20)The visible wavelengths are essential to a normal colour vision, however overexposure of high-energy visible (HEV) light may be damaging to both ocular and non-ocular health. Some health concerns associated with HEV light ... -
Optimization of Mucoadhesive Polymer Micelles for Drug Delivery and Ophthalmic Formulations
(University of Waterloo, 2019-08-29)Nanotechnology enable medicine (nanomedicine) is expected to be the next advent of the health care market, facilitating efficient, safe, and personalized therapies. But there has been limited success penetrating the market. ... -
Polymeric Coatings for Targeted Nanoparticle Delivery to Subsurface Contaminants
(University of Waterloo, 2019-05-01)Terrestrial oil spills account for the majority of oil spills world wide and present a challenging remediation problem owing to the inaccessibility of subsurface petroleum hydrocarbons (PHC). Contaminants such as crude oil ... -
Recyclable Photocatalysts for Oil Sands Process-Affected Water Treatment
(University of Waterloo, 2018-05-09)One of the largest environmental challenges faced by Canada is the cleanup and reclamation of land and water impacted by mining operations in the Athabasca oil sands. The persistence of toxicity associated with the soluble ... -
Synthesis of Polymeric Nanoparticles for the Controlled Release of Hydrophobic and Hydrophillic Theraputic Compounds
(University of Waterloo, 2016-09-01)Polymeric nanoparticle (NP) drug carriers present a promising technology for controlled release since they are capable of improving the encapsulation efficiency and stability of the drugs inside the NPs and also able to ...