Browsing University of Waterloo by Subject "transactivation"
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An Exploration of the Scope of GPCR to RTK Transactivation in HT22 and SH-SY5Y cells
(University of Waterloo, 2022-09-02)Receptor tyrosine kinase (RTK) transactivation is a mechanism by which G proteincoupled receptor (GPCR) activity induces the activation of an RTK. As separate families of receptors, they were long thought to act ... -
Transactivation of platelet-derived growth factor receptor type β: Mechanisms and potential relevance in neurobiology
(University of Waterloo, 2013-12-23)In the absence of ligand, certain growth factor receptors can be activated via G protein-coupled receptor (GPCR) activation in a process termed transactivation. Serotonin (5-HT) receptors can transactivate the receptor ...