Browsing University of Waterloo by Subject "tafazzin"
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Investigation of a potential therapeutic role for N-oleoylethanolamide and N-linoleoylethanolamide using lymphoblasts deficient in Tafazzin
(University of Waterloo, 2020-09-01)Barth syndrome (BTHS) is a rare X-linked genetic disorder caused by mutations in the TAZ gene that encodes for a cardiolipin (CL) remodelling enzyme, Tafazzin. Due to an inability to remodel the fatty acyl chains on CL ... -
Phenotypic Characterization of the Male Tafazzin-Knockout Mouse Model of Barth Syndrome at 3-, 6-, and 12-Months of Age
(University of Waterloo, 2022-05-18)Barth Syndrome (BTHS) is a devastating disorder caused by mutations in the gene encoding for Tafazzin (TAZ), a key enzyme involved in the biosynthesis of the phospholipid cardiolipin, which is vital for maintaining the ...