Browsing University of Waterloo by Subject "protein aggregation"
Now showing items 1-3 of 3
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Cellular Inclusion Bodies: Structure and Mechanisms
(University of Waterloo, 2022-08-18)Inclusion bodies (IBs) are insoluble aggregate structures that commonly form upon overexpression of proteins in heterologous hosts with relevance to biomedicine and biotechnology. These structures are of broad interest in ... -
Predicting and Measuring Molecular Mechanisms of Protein Aggregation
(University of Waterloo, 2011-08-30)Protein aggregation is a hallmark of a number of neurodegenerative disorders including Alzheimer’s Disease, Huntington’s Disease, and Amyotrophic Lateral Sclerosis. Despite the common occurrence of protein aggregation in ... -
Structural characterization and engineering of Adnectin inclusion bodies
(University of Waterloo, 2022-08-15)Protein aggregation is a fundamental process occurring as a response to aging, disease, protein overexpression and in many areas of biotechnology and medical applications. There has been much recent progress in determining ...