Browsing University of Waterloo by Subject "nitric oxide synthase"
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In vitro studies of NOS inhibitors using purified human NOS isozymes
(University of Waterloo, 2017-12-18)Endogenous nitric oxide (NO) is derived from L-arginine via a chemical reaction catalyzed by nitric oxide synthases (NOS). Three NOS isozymes are found in humans: neuronal NOS (nNOS), endothelial NOS (eNOS) and inducible ... -
Structural Investigation of Melatonin and its Metabolites as Possible Calmodulin Antagonists
(University of Waterloo, 2020-09-11)Calmodulin (CaM) is a small, highly conserved and ubiquitous calcium (Ca2+)-sensing protein that coordinates signal transduction through interactions with over 300 target molecules. It is composed of N- and C-terminal ...