Browsing University of Waterloo by Subject "Phosphoenolpyruvate carboxykinase"
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Functional consequences of changing structure, dynamics, and free-energy landscapes of phosphoenolpyruvate carboxykinases
(University of Waterloo, 2020-09-21)The complex relationship between structure, dynamics, and function will afford insights into the operational details of enzymes. To understand, regulate, and create enzymes, this complex nature must be comprehensively ... -
Inhibition of Phosphoenolpyruvate Carboxykinase with a 3-Mercaptopicolinic acid Analogue
(University of Waterloo, 2016-09-01)Phosphoenolpyruvate carboxykinase (PEPCK) is the metabolic enzyme that catalyzes the first committed step in gluconeogenesis and glyceroneogensis. More recently, PEPCK has been implicated in the maintenance and establishment ...