Browsing University of Waterloo by Author "Won, Gah-Jone"
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The Development of an Antibody-Drug Conjugate to Specifically Target and Soften the Crystalline Lens in vivo
Won, Gah-Jone (University of Waterloo, 2017-04-04)Helmholtz’s classical theory of accommodation states that, within the eye, contraction of the annular ciliary muscle releases the passive tension of zonules that hold the lens in a flattened state. As a result, the surface ... -
The effects of actomyosin disruptors on the mechanical integrity of the avian crystalline lens
Won, Gah-Jone; Fudge, Douglas S.; Choh, Vivian Cheng-Pei (Molecular Vision, 2015-01-27)Actin and myosin within the crystalline lens maintain the structural integrity of lens fiber cells and form a hexagonal lattice cradling the posterior surface of the lens. The actomyosin network was pharmacologically ...