Browsing University of Waterloo by Author "Hui, Alex"
Now showing items 1-4 of 4
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Acetic and Acrylic Acid Molecular Imprinted Model Silicone Hydrogel Materials for Ciprofloxacin-HCl Delivery
Hui, Alex; Sheardown, Heather; Jones, Lyndon W. (Multidisciplinary Digital Publishing Institute, 2012-01-02)Contact lenses, as an alternative drug delivery vehicle for the eye compared to eye drops, are desirable due to potential advantages in dosing regimen, bioavailability and patient tolerance/compliance. The challenge has ... -
Contact Lenses for Ciprofloxacin Drug Delivery
Hui, Alex (University of Waterloo, 2014-07-31)PURPOSE The purpose of this thesis was to evaluate the potential of contact lenses as ciprofloxacin drug delivery devices. METHODS Investigations into ciprofloxacin uptake and release characteristics, and the possibility ... -
In Vitro and In Vivo Evaluation of Novel Ciprofloxacin-Releasing Silicone Hydrogel Contact Lenses
Hui, Alex; Willcox, Mark D. P.; Jones, Lyndon W. (Association for Research in Vision and Ophthalmology, 2014-08-08)Purpose.: The purpose of this study was to evaluate ciprofloxacin-releasing silicone hydrogel contact lens materials in vitro and in vivo for the treatment of microbial keratitis. Methods.: Model silicone hydrogel contact ... -
Release of Ciprofloxacin-HCl and Dexamethasone Phosphate by Hyaluronic Acid Containing Silicone Polymers
Nguyen, Darrene; Hui, Alex; Weeks, Andrea; Heynen, Miriam L.; Joyce, Elizabeth; Sheardown, Heather; Jones, Lyndon W. (Multidisciplinary Digital Publishing Institute, 2012-04-19)The purpose of this study was to determine the effect of the covalent incorporation of hyaluronic acid (HA) into conventional hydrogel and hydrogels containing silicone as models for contact lens materials on the uptake ...