Browsing University of Waterloo by Author "Jacobi, Zachary E."
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Metal-Induced Specific and Nonspecific Oligonucleotide Folding Studied by FRET and Related Biophysical and Bioanalytical Implications
Kiy, Mehmet Murat; Jacobi, Zachary E.; Liu, Juewen (Wiley, 2012-01-13)Metal induced nucleic acid folding has been extensively studied with ribozymes, DNAzymes, tRNA and riboswitches. These RNA/DNA molecules usually have a high content of double-stranded regions to support a rigid scaffold. ... -
Visual detection of lead(II) using a label-free DNA-based sensor and its immobilization within a monolithic hydrogel
Jacobi, Zachary E.; Li, Lu; Liu, Juewen (Royal Society of Chemistry, 2012-02-07)Lead is highly toxic and its detection has attracted a lot of research interests. In recent years, DNA has been used for Pb2+ recognition and many fluorescent sensors with low to sub-nM detection limits have been reported. ...