Now showing items 1-2 of 2

    • The Design of Intervention Trials Involving Recurrent and Terminal Events 

      Wu, Longyang; Cook, Richard J. (Springer, 2013)
      Clinical trials are often designed to assess the effect of therapeutic interventions on the incidence of recurrent events in the presence of a dependent terminal event such as death. Statistical methods based on multistate ...
    • Marginal Methods for Multivariate Time to Event Data 

      Wu, Longyang (University of Waterloo, 2012-04-30)
      This thesis considers a variety of statistical issues related to the design and analysis of clinical trials involving multiple lifetime events. The use of composite endpoints, multivariate survival methods with dependent ...

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