Browsing University of Waterloo by Author "Wu, Longyang"
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The Design of Intervention Trials Involving Recurrent and Terminal Events
Wu, Longyang; Cook, Richard J. (Springer, 2013)Clinical trials are often designed to assess the effect of therapeutic interventions on the incidence of recurrent events in the presence of a dependent terminal event such as death. Statistical methods based on multistate ... -
Marginal Methods for Multivariate Time to Event Data
Wu, Longyang (University of Waterloo, 2012-04-30)This thesis considers a variety of statistical issues related to the design and analysis of clinical trials involving multiple lifetime events. The use of composite endpoints, multivariate survival methods with dependent ...