Browsing University of Waterloo by Author "Jeon, Chanil"
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Effects of molecular crowding and confinement on the spatial organization of a biopolymer
Jeon, Chanil; Jung, Youngkyun; Ha, Bae-Yeun (Royal Society of Chemistry, 2016-10-25)A chain molecule can be entropically collapsed in a crowded medium in a free or confined space. Here, we present a unified view of how molecular crowding collapses a flexible polymer in three distinct spaces: free, ... -
How are molecular crowding and the spatial organization of a biopolymer interrelated
Jeon, Chanil; Hyeon, Changbong; Jung, Youngkyun; Ha, Bae-Yeun (Royal Society of Chemistry, 2016-10-21)In a crowded cellular interior, dissolved biomolecules or crowders exert excluded volume effects on other biomolecules, which in turn control various processes including protein aggregation and chromosome organization. As ... -
A ring-polymer model shows how macromolecular crowding controls chromosome-arm organization in Escherichia coli
Jeon, Chanil; Jung, Youngkyun; Ha, Bae-Yeun (Nature Publishing Group, 2017-09-19)Macromolecular crowding influences various cellular processes such as macromolecular association and transcription, and is a key determinant of chromosome organization in bacteria. The entropy of crowders favors compaction ...