Now showing items 1-6 of 6

    • Antifungal ocular drug delivery via contact lenses using a novel in vitro eye model 

      Phan, Chau-Minh (University of Waterloo, 2016-04-21)
      Purpose: The purpose of this thesis was to evaluate the potential of contact lenses (CLs) as an antifungal drug delivery device, and to develop an in vitro eye model to test thereof. Methods: The first three chapters ...
    • Cellular changes at the lid margin 

      Muntz, Alex (University of Waterloo, 2017-11-28)
      PURPOSE: The hypothesis underlying this thesis is that CL wear, lid wiper epitheliopathy (LWE), and symptoms of dryness and discomfort may be manifest as cellular changes of the lid marginal epithelium, as a result of ...
    • Contact Lenses and Tear Film Lipids. 

      Walther, Hendrik (University of Waterloo, 2017-12-20)
      Introduction Lipids are essential tear components that aid the stability of the tear film (TF) to protect it from excess evaporation. The composition, conformation, and function of TF lipids are jeopardized by external ...
    • Contemporary Diagnosis and Management of Dry Eye 

      Ngo, William (University of Waterloo, 2016-08-31)
      Introduction Dry eye (DE) disease is characterized by symptoms including, but not limited to, ocular stinging, burning, and tearing. The symptoms can range from being mildly irritating, to severely debilitating and ...
    • Development of a topical ocular drug delivery system using polymeric nanoparticles 

      Liu, Shengyan (University of Waterloo, 2016-04-01)
      Common eye diseases such as dry eye syndrome affect 15% of the population. Although eye drops are the most common treatment for these diseases, over 95% of the drugs applied through eye drops are quickly cleared away due ...
    • In Vitro Cornea Models in Contact Lens Based Ocular Drug Delivery 

      Mohammadi, Saman (University of Waterloo, 2016-07-28)
      The development of suitable in vitro release and diffusion models for contact lens-based drug delivery may lead to the establishment of in vitro/in vivo correlations. It is evident that an in vitro model that can reproduce ...

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